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Pathway-Directed Screen for Dual PI3K/mTOR Inhibitors

PI3K/mTOR Inhibitor

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Hello world!

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September 7, 2021

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In the malarial parasite, pyrimidine biosynthesis provides the only route to these essential metabolites, as the parasite is unable to scavenge preformed pyrimidines (11C13)
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Abbreviations: CON, control; CANA, canagliflozin; AMPK, AMP-activated proteins kinase; ACC, acetyl-CoA carboxylase
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Results of ethnicities suggest that Dll1 enhances Ig secretion, while Jg1 has an inhibitory part(Santos recently demonstrated that Notch signaling protects germinal center (GC) B cells from apoptosis

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